Title:
A Phase 3, Randomized, Double blind, Placebo controlled, Multicenter Study of Bendamustine and Rituximab (BR) Alone Versus in Combination with Acalabrutinib (ACP 196) in Subjects with Previously Untreated Mantle Cell Lymphoma View
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: III
Title:
Association of Patient Activation with the Health-Related Quality of Life of Pancreatic Cancer Patients View
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Canton
Title:
STAR Ph1 CX-4945 Basal Cell Carcinoma View
Description: A Phase I Multi-Center Open-Label Treatment Duration Increment Expansion Safety and Pharmacodynamic Study of CX-4945 Administered Orally Twice Daily to Patients with Advanced Basal Cell Carcinoma (CX-4945-07)
Indication:
Skin Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 Pembro HR+/HER2- BC View
Description: A Randomized Double-Blind Phase III Study of Pembrolizumab versus Placebo in Combination with Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy for the Treatment of High-Risk Early-Stage Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK3475-KN756)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 TSR-042 Niraparib Ovarian FIRST View
Description: 3000-03-005/ENGOT-OV44 : A RANDOMIZED DOUBLE-BLIND PHASE 3 COMPARISON OF PLATINUM-BASED THERAPY WITH TSR-042 AND NIRAPARIB VERSUS STANDARD OF CARE PLATINUM-BASED THERAPY AS FIRST-LINE TREATMENT OF STAGE III OR IV NONMUCINOUS EPITHELIAL OVARIAN CANCER
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 TSR-042 Niraparib Ovarian FIRST View
Description: 3000-03-005/ENGOT-OV44 : A RANDOMIZED DOUBLE-BLIND PHASE 3 COMPARISON OF PLATINUM-BASED THERAPY WITH TSR-042 AND NIRAPARIB VERSUS STANDARD OF CARE PLATINUM-BASED THERAPY AS FIRST-LINE TREATMENT OF STAGE III OR IV NONMUCINOUS EPITHELIAL OVARIAN CANCER
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 TSR-042 Niraparib Ovarian FIRST View
Description: 3000-03-005/ENGOT-OV44 : A RANDOMIZED DOUBLE-BLIND PHASE 3 COMPARISON OF PLATINUM-BASED THERAPY WITH TSR-042 AND NIRAPARIB VERSUS STANDARD OF CARE PLATINUM-BASED THERAPY AS FIRST-LINE TREATMENT OF STAGE III OR IV NONMUCINOUS EPITHELIAL OVARIAN CANCER
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Atezo Rollover for GNE & Roche View
Description: BO39633 (IMbrella A) An open-Label Multicenter Extension and Long-Term Observational Study in Patients Previously Enrolled in A Genentech- and/or F.Hoffman-La Roche Ltd. sponsored Atezolizumab Study
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: II/III
Title:
PANOVA-3: 1L Gemcit + nab-pac pancreatic View
Description: PANOVA-3: Pivotal randomized open-label study of Tumor Treating Fields (TTFields 150kHz) concomitant with gemcitabine and nab-paclitaxel for front-line treatment of locally-advanced pancreatic adenocarcinoma (EF-27)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 FGFR erdafitinib urothelial View
Description: (42756493BLC3001) A Phase 3 Study of Erdafitinib Compared with Vinflunine or Docetaxel or Pembrolizumab in Subjects with Advanced Urothelial Cancer and Selected FGFR Gene Aberrations (THOR)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Rucaparib v PhysC mCRPC (TRITON3) View
Description: TRITON3: A Multicenter Randomized Open-label Phase 3 Study of Rucaparib versus Physician's Choice of Therapy for Patients withMetastatic Castration-resistant Prostate Cancer Associated withHomologous Recombination Deficiency (CO-338-063)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
FLEX Registry: Evaluate New Gene Express View
Description: MammaPrint BluePrint and Full-genome Data Linked with Clinical Data to Evaluate New Gene EXpression Profiles: An Adaptable Registry (FLEX Registry)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Title:
Ph3 Rituximab +/- Ibrutinib tx-naive FL View
Description: A Multicenter Randomized Double-blind Placebo-controlled Phase 3 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Combination with Rituximab versus Placebo in Combination with Rituximab in Treatment Naïve Subjects with Follicular Lymphoma - PCYC-1141-CA
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph4 Ixazomib+Lena & Dex MM (MM-6) View
Description: C16038: An Open-Label Single-Arm Multicenter Study to Evaluate the Effectiveness and Safety of Ixazomib (NINLARO®) in Combination with Lenalidomide and Dexamethasone (IRD) in Patients with Multiple Myeloma Previously Receiving a Bortezomib-Based Triplet Induction Regimen (Phase IV)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: IV
Title:
STAR BV in pts w/1L cHL or PTCL View
Description: (SGN35-015) A phase 2 open-label study of brentuximab vedotin in front-line therapy of Hodgkin lymphoma (HL) and CD30-expressing peripheral T-cell lymphoma (PTCL) in older patients or patients with significant comorbidities ineligible for standard chemotherapy
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
TGR-1202 +/- Ublituximab in NHL View
Description: A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 with or without Bendamustine and TGR-1202 alone in Patients with Previously Treated Non-Hodgkin's Lymphoma (UTX-TGR-205)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph3 Nirap+Abirat+Pred mCRPC View
Description: A Phase 3 Randomized Placebo-controlled Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Subjects with Metastatic Prostate Cancer(64091742PCR3001)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1/2 FIH BMS-986249 + Nivo Solid Tumor View
Description: A Phase 1/2 First-in-Human Study of BMS-986249 Alone and in Combination with Nivolumab in Advanced Solid Tumors
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I
Title:
STAR Sitra+Nivo/Pembro+Enfor Adv/Met Uro View
Description: A Phase 2 Study of Sitravatinib in Combination with PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma (516-003)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Sitra+Nivo/Pembro+Enfor Adv/Met Uro View
Description: A Phase 2 Study of Sitravatinib in Combination with PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma (516-003)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph1/2 BLU667 thy NSCLC Sol tum View
Description: A Phase 1/2 Study of the Highly-selective RET Inhibitor BLU-667 in Patients with Thyroid Cancer Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 BLU667 thy NSCLC Sol tum View
Description: A Phase 1/2 Study of the Highly-selective RET Inhibitor BLU-667 in Patients with Thyroid Cancer Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 BLU667 thy NSCLC Sol tum View
Description: A Phase 1/2 Study of the Highly-selective RET Inhibitor BLU-667 in Patients with Thyroid Cancer Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
Indication:
Thyroid Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
Ph1/2 INCB001158 + SC Dara vs Dara SC MM View
Description: A Randomized Open-Label Phase 1/2 Study of INCB001158Combined With Subcutaneous (SC) Daratumumab Compared toDaratumumab SC in Participants With Relapsed or RefractoryMultiple Myeloma (INCB 01158-206)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: I/II
Title:
Biomarker Advcd Uro Cncer and FGFR Aber View
Description: Biomarker Study to Identify Subjects with Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations (42756493BLC0002)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: IV
Title:
Biomarker Advcd Uro Cncer and FGFR Aber View
Description: Biomarker Study to Identify Subjects with Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations (42756493BLC0002)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: IV
Title:
TTFlds cncmnt w/ PTX recurrent ovn cnr View
Description: ENGOT-ov50 / INNOVATE-3: Pivotal Randomized Open-Label Study ofTumor Treating Fields (TTFields 200kHz) Concomitant with WeeklyPaclitaxel for the Treatment of Recurrent Ovarian Cancer
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph 1/1b Immunotherapy Combo in NSCLC View
Description: (AB928CSP0004) A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants with Lung Cancer
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Zanu in Ibrut/Acala intolerant B-Cell View
Description: A Phase 2 Multicenter Single-arm Study of Zanubrutinib (BGB-3111) in Patients with Previously Treated B-Cell Lymphoma Intolerant of Prior Treatment with Ibrutinib and/or Acalabrutinib (BGB-3111-215)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: II
Title:
Zanu in Ibrut/Acala intolerant B-Cell View
Description: A Phase 2 Multicenter Single-arm Study of Zanubrutinib (BGB-3111) in Patients with Previously Treated B-Cell Lymphoma Intolerant of Prior Treatment with Ibrutinib and/or Acalabrutinib (BGB-3111-215)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 3 Sit+Nivo vs. Docetaxel NSCLC View
Description: 516-005: A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 rib+non-sterAIs HR+HER2- BC (AMELEE) View
Description: A phase II multicenter randomized open-label study to evaluate the safety and efficacy of 400 mg of ribociclib in combination with non-steroidal aromatase inhibitors for the treatment of pre- and postmenopausal women with hormone receptor-positive HER2-negative advanced breast cancer who received no prior therapy for advanced disease (CLEE011A2207)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Infigratinib vs Gem/Cis Cholangio View
Description: A Phase 3 Multicenter Open-Label Randomized Controlled Study of Oral Infigratinib versus Gemcitabine with Cisplatin in Subjects with Advanced/Metastatic or Inoperable Cholangiocarcinoma with FGFR2 Gene Fusions/Translocations: The PROOF Trial (QBGJ398-301)
Indication:
Biliary Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 Cervical 2L (RaPiDS) View
Description: A Two-arm Randomized Non-comparative Phase 2 Trial of AGEN2034(anti-PD-1) as a Monotherapy or Combination Therapy with AGEN1884(anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer(Second Line) - RaPiDS (C-750-01/GOG-3028)
Indication:
Cervical Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 1/1b TNBC Ovarian View
Description: (AB928CSP0002) A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants with Breast or Gynecologic Malignancies
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Ph3 R/R MM (DREAMM 3) View
Description: 207495: A Phase III Open-Label Randomized Study to Evaluate the Efficacy and Safety of Single Agent Belantamab Mafodotin Compared to Pomalidomide plus Low-dose Dexamethasone (pom/dex) in Participants with Relapsed/Refractory Multiple Myeloma (RRMM) (DREAMM3)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 R/R MM (DREAMM 7) View
Description: DREAMM 7: A Multicenter Open-Label Randomized Phase III Study to Evaluate the Efficacy and Safety of the Combination of Belantamab Mafodotin Bortezomib and Dexamethasone (B-Vd) Compared with the Combination of Daratumumab Bortezomib and Dexamethasone (D-Vd) in Participants with Relapsed/Refractory Multiple Myeloma (207503)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1/2 AGEN1884 Adv Refractory cancer View
Description: A Phase 1/2 Open-Label Multicenter Study to Evaluate the Safety Pharmacokinetics andPharmacodynamics of an Anti¨CCTLA-4 Human Monoclonal Antibody (AGEN1884)in Subjects with Advanced or Refractory Cancer and in Subjects who have Progressed During Treatment with a PD-1/PD-L1 Inhibitor as their Most Recent Therapy (C-500-01)
Indication:
Liver Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
Ph3b Venetoclax AML View
Description: A Phase 3b Single-Arm Multicenter Open-Label Study of Venetoclax in Combination with Azacitidine or Decitabine in an Outpatient Setting in AML Patients Ineligible for Intensive Chemotherapy (M19-072)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 JCAR017 R/R NHL View
Description: A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-017007)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 R/R CLL/SLL View
Description: A Phase 3 Randomized Study of Zanubrutinib (BGB-3111) Compared with Ibrutinib in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (BGB-3111-305)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 R/R CLL/SLL View
Description: A Phase 3 Randomized Study of Zanubrutinib (BGB-3111) Compared with Ibrutinib in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (BGB-3111-305)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 ALK+ mNSCLC (Brigatinib-3001) View
Description: Brigatinib-3001- A Phase 3 Randomized Open-label Study of Brigatinib (ALUNBRIG®)Versus Alectinib (ALECENSA®) in Advanced Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer Patients Who Have Progressed on Crizotinib (XALKORI®)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Anal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Biliary Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Bone Mets
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Brain Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Uterine Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Vaginal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Vulvar Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Rectal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Renal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Sarcoma
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Testicular Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Thyroid Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Malignant Adenoma
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Penile Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Gastric Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Head and Neck Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Kaposi's Sarcoma
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Kidney Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Liver Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Cervical Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Endometrial Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Esophageal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Gall Bladder Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph2 Erdafitinib FGFR Solid Tumors View
Description: A Phase 2 Study of Erdafitinib in Subjects With Advanced Solid Tumors and FGFR Gene Alterations (42756493CAN2002)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 1b FIH XMT-1536 Solid Tumor NaPi2b View
Description: A Phase 1b First-in-Human Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b (MER-XMT-1536-1)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Ph 1b FIH XMT-1536 Solid Tumor NaPi2b View
Description: A Phase 1b First-in-Human Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b (MER-XMT-1536-1)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Ph 1b/ 3 Taze w/ R2 R/R Fol Lymph View
Description: A PHASE 1B/3 DOUBLE-BLIND RANDOMIZED ACTIVE-CONTROLLED 3-STAGE BIOMARKER ADAPTIVE STUDY OF TAZEMETOSTAT OR PLACEBO IN COMBINATION WITH LENALIDOMIDE PLUS RITUXIMAB IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA (EZH-302)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: I
Title:
EAP BGB-3111 B-Cell Malig View
Description: A Single-Arm Expanded Access Study of Zanubrutinib (BGB-3111) in Patients with B-cell Malignancies (BGB-3111-216)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Title:
Ph 3 Nivo vs. Plac Hepatocell Carc View
Description: A Phase 3 Randomized Double-blind Study of Adjuvant Nivolumab versus Placebo for Participants with Hepatocellular Carcinoma Who Are at High Risk of Recurrence after Curative Hepatic Resection or Ablation (CA209-9DX)
Indication:
Liver Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1 FIH TP-1287 Solid tumor View
Description: A Phase I First-in-human Open-label Dose-escalation Safety Pharmacokinetic and Pharmacodynamic Study of Oral TP-1287 Administered Twice Daily for 14 Days to Patients with Advanced Solid Tumors (TP-1287-101)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I
Title:
STAR Ph 3 Tuca/Placbo + T-DM1 HER2+ View
Description: STAR: Randomized double-blind phase 3 study of tucatinib or placebo in combination with ado-trastuzumab emtansine (T-DM1) for subjects with unresectable locally-advanced or metastatic HER2+ breast cancer (HER2CLIMB-02)(SGNTUC-016)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph2 Pemigatinib Solids FGFR View
Description: (INCB 54828-207) A Phase 2 Open-Label Single-Arm Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR PH3 Pacritinib vs MD choice in MF View
Description: A Randomized Controlled Phase 3 Study of Pacritinib Versus Physician's Choice in Patients with Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis with Severe Thrombocytopenia (Platelets Counts <50000/µL) (PAC203)
Indication:
Essential Thrombocythemia
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR PH3 Pacritinib vs MD choice in MF View
Description: A Randomized Controlled Phase 3 Study of Pacritinib Versus Physician's Choice in Patients with Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis with Severe Thrombocytopenia (Platelets Counts <50000/µL) (PAC203)
Indication:
Myelofibrosis
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph 3 Infigratinib UC w/ FGFR3 Alt View
Description: QBGJ398-302: Phase 3 Multicenter Double-Blind Randomized Placebo-Controlled Trial of Infigratinib for the Adjuvant Treatment of Subjects with Invasive Urothelial Carcinoma with Susceptible FGFR3 Genetic Alterations (PROOF302)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 GDC0077+Palbo+Fulv vs Placebo PIK3CA View
Description: A PHASE III RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF GDC-0077 PLUS PALBOCICLIB AND FULVESTRANT VERSUS PLACEBO PLUS PALBOCICLIB AND FULVESTRANT IN PATIENTS WITH PIK3CA-MUTANT HOROMONE RECEPTOR-POSITIVE HER2-NEGATIVE LOCALLY ADVANCED OR METASTATIC BREAST CANCER (WO41554)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph 3 BYL719 + nabpax TNBC PIK3CA View
Description: EPIK-B3: A phase III multicenter randomized double-blind placebo-controlled study to assess the efficacy and safety of alpelisib (BYL719) in combination with nab-paclitaxel in patients with advanced triple negative breast cancer with either phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) mutation or phosphatase and tensin homolog protein (PTEN) loss without PIK3CA mutation (CBYL719H12301)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph 3 NUC-1031+Cis vs Gem/Cis la/mBTC View
Description: A Phase III Open-Label Multi-Centre Randomised Study Comparing NUC-1031 plus Cisplatin to Gemcitabine plus Cisplatin in Patients with Previously Untreated Locally Advanced or Metastatic Biliary Tract Cancer (NuTide:121)
Indication:
Biliary Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 Sinti vs Placebo ESCC View
Description: A Multicenter Double-Blind Randomized Phase III Clinical Trial Evaluating the Efficacy and Safety of Sintilimab vs. Placebo in Combination with Chemotherapy for First-Line Treatment of Unresectable Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma (ORIENT-15)CIBI308A301
Indication:
Esophageal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1b Ipatasertib + Atezo + Docetax mCRPC View
Description: A PHASE Ib OPEN-LABEL MULTICENTER STUDY EVALUATING THE SAFETY AND EFFICACY OF IPATASERTIB IN COMBINATION WITH ATEZOLIZUMAB AND DOCETAXEL IN METASTATIC CASTRATE RESISTANT PROSTATE CANCER (CO41792)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Plasma test ColoRec Cancer View
Description: PREEMPT CRC: PREvention Employing a Multiomics Plasma-based Test for ColoRectal Cancer (FRNM-004)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Title:
Ph2 m7824 triple neg BC View
Description: (MS200647_0020) A Phase II Multicenter Open Label Study of Bintrafusp alfa (M7824) Monotherapy in Participants with HMGA2-expressing Triple Negative Breast Cancer
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 Mirv Sora Epi Ova FTC View
Description: SORAYA: A Phase 3 Single Arm Study of Mirvetuximab Soravtansine in Advanced High-Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression (IMGN853-0417)
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 Mirv Sora Epi Ova FTC View
Description: SORAYA: A Phase 3 Single Arm Study of Mirvetuximab Soravtansine in Advanced High-Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression (IMGN853-0417)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 Mirv Sora Epi Ova FTC View
Description: SORAYA: A Phase 3 Single Arm Study of Mirvetuximab Soravtansine in Advanced High-Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression (IMGN853-0417)
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
PH3 Dara/Len vs Len NDMM View
Description: A Randomized Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Patients with Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant (54767414MMY3021)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: III
Title:
PH3 Plac Carbo Pacil Dura +/- Olap DUO-E View
Description: D9311C00001; GOG-3041; ENGOT-EN10: A Randomised Multicentre Double-blind Placebo-controlled Phase III Study of First-line Carboplatin and Paclitaxel in Combination with Durvalumab Followed by Maintenance Durvalumab with or without Olaparib in Patients with Newly Diagnosed Advanced or Recurrent Endometrial Cancer (DUO-E)
Indication:
Endometrial Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 Ublituximab+ Umbralisib+ Venetoc CLL View
Description: ULTRA-V: Phase 2 Study to Assess the Efficacy and Safety of Ublituximab in Combination with Umbralisib and Venetoclax (U2-V) in Subjects with Chronic Lymphocytic Leukemia (CLL)(U2-VEN-207)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 Fruq + Placebo CC (FRESCO-2) View
Description: A Global Multicenter Randomized Placebo-Controlled Phase 3 Trial to Compare the Efficacy and Safety of Fruquintinib Plus Best Supportive Care to Placebo Plus Best Supportive Care in Patients with Refractory Metastatic Colorectal Cancer (FRESCO-2) (2019-013-GLOB1)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR KEAP1/NRF2 NSCLC View
Description: CX-839-014 "KEAPSAKE": A Phase 2 Randomized Multicenter Double-blind Study of the Glutaminase Inhibitor Telaglenastat with Pembrolizumab and Chemotherapy versus Placebo with Pembrolizumab and Chemotherapy in First-line Metastatic KEAP1/NRF2-mutated Nonsquamous Non-Small Cell Lung Cancer (NSCLC)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR-PH3 pral(Blu-667) RET-fusion mNSCLC View
Description: A Randomized Open-Label Phase 3 Study of Pralsetinib versus Standard of Care for First Line Treatment of RET fusion-positive Metastatic Non-Small Cell Lung Cancer (BLU-667-2303)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Biomarker DNA Defect Men Prostate View
Description: Biomarker Study to Determine Frequency of DNA-repair Defects in Men with Metastatic Prostate Cancer (64091742PCR0002)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Title:
Ph 3 Chemo +/- Pembro/Olap EOC View
Description: A Randomized Phase 3 Double-Blind Study of Chemotherapy With or Without Pembrolizumab Followed by Maintenance With Olaparib or Placebo for the First-Line Treatment of BRCA non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK7339-001/ENGOT-ov43/GOG-3036)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
PH3 Ven+G vs FCR/BR in Fit untreated CLL View
Description: A PROSPECTIVE OPEN-LABEL MULTICENTER RANDOMIZED PHASE III TRIAL TO COMPARE THE EFFICACY AND SAFETY OF A COMBINED REGIMEN OF OBINUTUZUMAB AND VENETOCLAX VERSUS FLUDARABINE CYCLOPHOSPHAMIDE AND RITUXIMAB (FCR)/ BENDAMUSTINE AND RITUXIMAB (BR) IN FIT PATIENTS WITH PREVIOUSLY UNTREATED CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) WITHOUT DEL (17P) OR TP53 MUTATION (CO41685)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: III
Title:
PH2 MM Carf Poma & dexa (KPd) View
Description: An Open-label Phase 2 Study Treating Subjects With First or Second Relapse of Multiple Myeloma with Carfilzomib Pomalidomide and Dexamethasone (KPd) (20180117)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 3 Irino Oxa Flu Leu Pac + GEM mPan View
Description: An open-label randomised multicentre phase III study of irinotecan liposome injection oxaliplatin 5-fluorouracil/leucovorin versus nab-paclitaxel plus gemcitabine in subjects who have not previously received chemotherapy for metastatic adenocarcinoma of the pancreas (D-US-60010-001)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR: PH2 Tuca+ Tras HER2+ CC View
Description: MOUNTAINEER: A Phase 2 Open Label Study of Tucatinib Combined with Trastuzumab in Patients with HER2+ Metastatic Colorectal Cancer (ACCRU-GI-1617 SGNTUC-017)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR: PH2 Tuca+ Tras HER2+ CC View
Description: MOUNTAINEER: A Phase 2 Open Label Study of Tucatinib Combined with Trastuzumab in Patients with HER2+ Metastatic Colorectal Cancer (ACCRU-GI-1617 SGNTUC-017)
Indication:
Rectal Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
PH2 Brentux+CHP In Tx Naive PTCL View
Description: A dual-cohort open-label phase 2 study of brentuximab vedotin and CHP (A+CHP) in the frontline treatment of subjects with peripheral T-cell lymphoma (PTCL) with less than 10% CD30 expression (SGN35-032)
Indication:
Hematologic
Location:
Texas Oncology-Canton
Phase: II
Title:
PH2 Brentux+CHP In Tx Naive PTCL View
Description: A dual-cohort open-label phase 2 study of brentuximab vedotin and CHP (A+CHP) in the frontline treatment of subjects with peripheral T-cell lymphoma (PTCL) with less than 10% CD30 expression (SGN35-032)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: II
Title:
PH2 Brentux+CHP In Tx Naive PTCL View
Description: A dual-cohort open-label phase 2 study of brentuximab vedotin and CHP (A+CHP) in the frontline treatment of subjects with peripheral T-cell lymphoma (PTCL) with less than 10% CD30 expression (SGN35-032)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph3 Carbo/Pac NCMGA00012 MSCC View
Description: A Phase 3 Global Multicenter Double-Blind Randomized Study of Carboplatin-Paclitaxel With INCMGA00012 or Placebo in Participants With Inoperable Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Anal Canal Not Previously Treated With Systemic Chemotherapy (POD1UM-303/InterAACT 2) (INCMGA 0012-303)
Indication:
Anal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 Carbo/Pac NCMGA00012 MSCC View
Description: A Phase 3 Global Multicenter Double-Blind Randomized Study of Carboplatin-Paclitaxel With INCMGA00012 or Placebo in Participants With Inoperable Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Anal Canal Not Previously Treated With Systemic Chemotherapy (POD1UM-303/InterAACT 2) (INCMGA 0012-303)
Indication:
Carcinoid
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR PH 2 ASG-22CE Urothelial Cancer View
Description: A study of enfortumab vedotin (ASG-22CE) as monotherapy or in combination with other anticancer therapies for the treatment of urothelial cancer (SGN22E-002)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR PH 2 ASG-22CE Urothelial Cancer View
Description: A study of enfortumab vedotin (ASG-22CE) as monotherapy or in combination with other anticancer therapies for the treatment of urothelial cancer (SGN22E-002)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR PH3 Nirap Abira HRR mCSPC View
Description: A Phase 3 Randomized Placebo-controlled Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants with Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)(67652000PCR3002)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph1 CX-4945 Basal Cell Carcinoma View
Description: A Phase I Multi-Center Open-Label Treatment Duration Increment Expansion Safety and Pharmacodynamic Study of CX-4945 Administered Orally Twice Daily to Patients with Advanced Basal Cell Carcinoma (CX-4945-07)
Indication:
Skin Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph2 A+AVD +G-CSF or AOAD in CHL View
Description: SGN35-027: Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 Pembro HR+/HER2- BC View
Description: A Randomized Double-Blind Phase III Study of Pembrolizumab versus Placebo in Combination with Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy for the Treatment of High-Risk Early-Stage Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK3475-KN756)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 TSR-042 Niraparib Ovarian FIRST View
Description: 3000-03-005/ENGOT-OV44 : A RANDOMIZED DOUBLE-BLIND PHASE 3 COMPARISON OF PLATINUM-BASED THERAPY WITH TSR-042 AND NIRAPARIB VERSUS STANDARD OF CARE PLATINUM-BASED THERAPY AS FIRST-LINE TREATMENT OF STAGE III OR IV NONMUCINOUS EPITHELIAL OVARIAN CANCER
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 TSR-042 Niraparib Ovarian FIRST View
Description: 3000-03-005/ENGOT-OV44 : A RANDOMIZED DOUBLE-BLIND PHASE 3 COMPARISON OF PLATINUM-BASED THERAPY WITH TSR-042 AND NIRAPARIB VERSUS STANDARD OF CARE PLATINUM-BASED THERAPY AS FIRST-LINE TREATMENT OF STAGE III OR IV NONMUCINOUS EPITHELIAL OVARIAN CANCER
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 TSR-042 Niraparib Ovarian FIRST View
Description: 3000-03-005/ENGOT-OV44 : A RANDOMIZED DOUBLE-BLIND PHASE 3 COMPARISON OF PLATINUM-BASED THERAPY WITH TSR-042 AND NIRAPARIB VERSUS STANDARD OF CARE PLATINUM-BASED THERAPY AS FIRST-LINE TREATMENT OF STAGE III OR IV NONMUCINOUS EPITHELIAL OVARIAN CANCER
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Atezo Rollover for GNE & Roche View
Description: BO39633 (IMbrella A) An open-Label Multicenter Extension and Long-Term Observational Study in Patients Previously Enrolled in A Genentech- and/or F.Hoffman-La Roche Ltd. sponsored Atezolizumab Study
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: II/III
Title:
PANOVA-3: 1L Gemcit + nab-pac pancreatic View
Description: PANOVA-3: Pivotal randomized open-label study of Tumor Treating Fields (TTFields 150kHz) concomitant with gemcitabine and nab-paclitaxel for front-line treatment of locally-advanced pancreatic adenocarcinoma (EF-27)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 FGFR erdafitinib urothelial View
Description: (42756493BLC3001) A Phase 3 Study of Erdafitinib Compared with Vinflunine or Docetaxel or Pembrolizumab in Subjects with Advanced Urothelial Cancer and Selected FGFR Gene Aberrations (THOR)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Rucaparib v PhysC mCRPC (TRITON3) View
Description: TRITON3: A Multicenter Randomized Open-label Phase 3 Study of Rucaparib versus Physician's Choice of Therapy for Patients withMetastatic Castration-resistant Prostate Cancer Associated withHomologous Recombination Deficiency (CO-338-063)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
FLEX Registry: Evaluate New Gene Express View
Description: MammaPrint BluePrint and Full-genome Data Linked with Clinical Data to Evaluate New Gene EXpression Profiles: An Adaptable Registry (FLEX Registry)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Title:
Ph3 Rituximab +/- Ibrutinib tx-naive FL View
Description: A Multicenter Randomized Double-blind Placebo-controlled Phase 3 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Combination with Rituximab versus Placebo in Combination with Rituximab in Treatment Naïve Subjects with Follicular Lymphoma - PCYC-1141-CA
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph4 Ixazomib+Lena & Dex MM (MM-6) View
Description: C16038: An Open-Label Single-Arm Multicenter Study to Evaluate the Effectiveness and Safety of Ixazomib (NINLARO®) in Combination with Lenalidomide and Dexamethasone (IRD) in Patients with Multiple Myeloma Previously Receiving a Bortezomib-Based Triplet Induction Regimen (Phase IV)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: IV
Title:
STAR BV in pts w/1L cHL or PTCL View
Description: (SGN35-015) A phase 2 open-label study of brentuximab vedotin in front-line therapy of Hodgkin lymphoma (HL) and CD30-expressing peripheral T-cell lymphoma (PTCL) in older patients or patients with significant comorbidities ineligible for standard chemotherapy
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
TGR-1202 +/- Ublituximab in NHL View
Description: A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 with or without Bendamustine and TGR-1202 alone in Patients with Previously Treated Non-Hodgkin's Lymphoma (UTX-TGR-205)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph3 Nirap+Abirat+Pred mCRPC View
Description: A Phase 3 Randomized Placebo-controlled Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Subjects with Metastatic Prostate Cancer(64091742PCR3001)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1/2 FIH BMS-986249 + Nivo Solid Tumor View
Description: A Phase 1/2 First-in-Human Study of BMS-986249 Alone and in Combination with Nivolumab in Advanced Solid Tumors
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I
Title:
STAR Sitra+Nivo/Pembro+Enfor Adv/Met Uro View
Description: A Phase 2 Study of Sitravatinib in Combination with PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma (516-003)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Sitra+Nivo/Pembro+Enfor Adv/Met Uro View
Description: A Phase 2 Study of Sitravatinib in Combination with PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma (516-003)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph1/2 BLU667 thy NSCLC Sol tum View
Description: A Phase 1/2 Study of the Highly-selective RET Inhibitor BLU-667 in Patients with Thyroid Cancer Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 BLU667 thy NSCLC Sol tum View
Description: A Phase 1/2 Study of the Highly-selective RET Inhibitor BLU-667 in Patients with Thyroid Cancer Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 BLU667 thy NSCLC Sol tum View
Description: A Phase 1/2 Study of the Highly-selective RET Inhibitor BLU-667 in Patients with Thyroid Cancer Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors
Indication:
Thyroid Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
Ph1/2 INCB001158 + SC Dara vs Dara SC MM View
Description: A Randomized Open-Label Phase 1/2 Study of INCB001158Combined With Subcutaneous (SC) Daratumumab Compared toDaratumumab SC in Participants With Relapsed or RefractoryMultiple Myeloma (INCB 01158-206)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: I/II
Title:
Biomarker Advcd Uro Cncer and FGFR Aber View
Description: Biomarker Study to Identify Subjects with Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations (42756493BLC0002)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: IV
Title:
Biomarker Advcd Uro Cncer and FGFR Aber View
Description: Biomarker Study to Identify Subjects with Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations (42756493BLC0002)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: IV
Title:
TTFlds cncmnt w/ PTX recurrent ovn cnr View
Description: ENGOT-ov50 / INNOVATE-3: Pivotal Randomized Open-Label Study ofTumor Treating Fields (TTFields 200kHz) Concomitant with WeeklyPaclitaxel for the Treatment of Recurrent Ovarian Cancer
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph 1/1b Immunotherapy Combo in NSCLC View
Description: (AB928CSP0004) A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants with Lung Cancer
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Zanu in Ibrut/Acala intolerant B-Cell View
Description: A Phase 2 Multicenter Single-arm Study of Zanubrutinib (BGB-3111) in Patients with Previously Treated B-Cell Lymphoma Intolerant of Prior Treatment with Ibrutinib and/or Acalabrutinib (BGB-3111-215)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: II
Title:
Zanu in Ibrut/Acala intolerant B-Cell View
Description: A Phase 2 Multicenter Single-arm Study of Zanubrutinib (BGB-3111) in Patients with Previously Treated B-Cell Lymphoma Intolerant of Prior Treatment with Ibrutinib and/or Acalabrutinib (BGB-3111-215)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 3 Sit+Nivo vs. Docetaxel NSCLC View
Description: 516-005: A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 rib+non-sterAIs HR+HER2- BC (AMELEE) View
Description: A phase II multicenter randomized open-label study to evaluate the safety and efficacy of 400 mg of ribociclib in combination with non-steroidal aromatase inhibitors for the treatment of pre- and postmenopausal women with hormone receptor-positive HER2-negative advanced breast cancer who received no prior therapy for advanced disease (CLEE011A2207)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Infigratinib vs Gem/Cis Cholangio View
Description: A Phase 3 Multicenter Open-Label Randomized Controlled Study of Oral Infigratinib versus Gemcitabine with Cisplatin in Subjects with Advanced/Metastatic or Inoperable Cholangiocarcinoma with FGFR2 Gene Fusions/Translocations: The PROOF Trial (QBGJ398-301)
Indication:
Biliary Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 Cervical 2L (RaPiDS) View
Description: A Two-arm Randomized Non-comparative Phase 2 Trial of AGEN2034(anti-PD-1) as a Monotherapy or Combination Therapy with AGEN1884(anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer(Second Line) - RaPiDS (C-750-01/GOG-3028)
Indication:
Cervical Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 1/1b TNBC Ovarian View
Description: (AB928CSP0002) A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants with Breast or Gynecologic Malignancies
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Ph3 R/R MM (DREAMM 3) View
Description: 207495: A Phase III Open-Label Randomized Study to Evaluate the Efficacy and Safety of Single Agent Belantamab Mafodotin Compared to Pomalidomide plus Low-dose Dexamethasone (pom/dex) in Participants with Relapsed/Refractory Multiple Myeloma (RRMM) (DREAMM3)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 R/R MM (DREAMM 7) View
Description: DREAMM 7: A Multicenter Open-Label Randomized Phase III Study to Evaluate the Efficacy and Safety of the Combination of Belantamab Mafodotin Bortezomib and Dexamethasone (B-Vd) Compared with the Combination of Daratumumab Bortezomib and Dexamethasone (D-Vd) in Participants with Relapsed/Refractory Multiple Myeloma (207503)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1/2 AGEN1884 Adv Refractory cancer View
Description: A Phase 1/2 Open-Label Multicenter Study to Evaluate the Safety Pharmacokinetics andPharmacodynamics of an Anti¨CCTLA-4 Human Monoclonal Antibody (AGEN1884)in Subjects with Advanced or Refractory Cancer and in Subjects who have Progressed During Treatment with a PD-1/PD-L1 Inhibitor as their Most Recent Therapy (C-500-01)
Indication:
Liver Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
Ph3b Venetoclax AML View
Description: A Phase 3b Single-Arm Multicenter Open-Label Study of Venetoclax in Combination with Azacitidine or Decitabine in an Outpatient Setting in AML Patients Ineligible for Intensive Chemotherapy (M19-072)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 JCAR017 R/R NHL View
Description: A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-017007)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 R/R CLL/SLL View
Description: A Phase 3 Randomized Study of Zanubrutinib (BGB-3111) Compared with Ibrutinib in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (BGB-3111-305)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 R/R CLL/SLL View
Description: A Phase 3 Randomized Study of Zanubrutinib (BGB-3111) Compared with Ibrutinib in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (BGB-3111-305)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 ALK+ mNSCLC (Brigatinib-3001) View
Description: Brigatinib-3001- A Phase 3 Randomized Open-label Study of Brigatinib (ALUNBRIG®)Versus Alectinib (ALECENSA®) in Advanced Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer Patients Who Have Progressed on Crizotinib (XALKORI®)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Anal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Biliary Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Bone Mets
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Brain Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Uterine Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Vaginal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Vulvar Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Rectal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Renal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Sarcoma
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Testicular Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Thyroid Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Malignant Adenoma
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Penile Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Gastric Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Head and Neck Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Kaposi's Sarcoma
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Kidney Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Liver Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Cervical Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Endometrial Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Esophageal Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph1/2 MRTX849 Solids KRAS G12C View
Description: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation (849-001)
Indication:
Gall Bladder Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR Ph2 Erdafitinib FGFR Solid Tumors View
Description: A Phase 2 Study of Erdafitinib in Subjects With Advanced Solid Tumors and FGFR Gene Alterations (42756493CAN2002)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 1b FIH XMT-1536 Solid Tumor NaPi2b View
Description: A Phase 1b First-in-Human Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b (MER-XMT-1536-1)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Ph 1b FIH XMT-1536 Solid Tumor NaPi2b View
Description: A Phase 1b First-in-Human Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b (MER-XMT-1536-1)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Ph 1b/ 3 Taze w/ R2 R/R Fol Lymph View
Description: A PHASE 1B/3 DOUBLE-BLIND RANDOMIZED ACTIVE-CONTROLLED 3-STAGE BIOMARKER ADAPTIVE STUDY OF TAZEMETOSTAT OR PLACEBO IN COMBINATION WITH LENALIDOMIDE PLUS RITUXIMAB IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA (EZH-302)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: I
Title:
EAP BGB-3111 B-Cell Malig View
Description: A Single-Arm Expanded Access Study of Zanubrutinib (BGB-3111) in Patients with B-cell Malignancies (BGB-3111-216)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Title:
Ph 3 Nivo vs. Plac Hepatocell Carc View
Description: A Phase 3 Randomized Double-blind Study of Adjuvant Nivolumab versus Placebo for Participants with Hepatocellular Carcinoma Who Are at High Risk of Recurrence after Curative Hepatic Resection or Ablation (CA209-9DX)
Indication:
Liver Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1 FIH TP-1287 Solid tumor View
Description: A Phase I First-in-human Open-label Dose-escalation Safety Pharmacokinetic and Pharmacodynamic Study of Oral TP-1287 Administered Twice Daily for 14 Days to Patients with Advanced Solid Tumors (TP-1287-101)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: I
Title:
STAR Ph 3 Tuca/Placbo + T-DM1 HER2+ View
Description: STAR: Randomized double-blind phase 3 study of tucatinib or placebo in combination with ado-trastuzumab emtansine (T-DM1) for subjects with unresectable locally-advanced or metastatic HER2+ breast cancer (HER2CLIMB-02)(SGNTUC-016)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph2 Pemigatinib Solids FGFR View
Description: (INCB 54828-207) A Phase 2 Open-Label Single-Arm Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)
Indication:
Solid Tumors
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR PH3 Pacritinib vs MD choice in MF View
Description: A Randomized Controlled Phase 3 Study of Pacritinib Versus Physician's Choice in Patients with Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis with Severe Thrombocytopenia (Platelets Counts <50000/µL) (PAC203)
Indication:
Essential Thrombocythemia
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR PH3 Pacritinib vs MD choice in MF View
Description: A Randomized Controlled Phase 3 Study of Pacritinib Versus Physician's Choice in Patients with Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis with Severe Thrombocytopenia (Platelets Counts <50000/µL) (PAC203)
Indication:
Myelofibrosis
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph 3 Infigratinib UC w/ FGFR3 Alt View
Description: QBGJ398-302: Phase 3 Multicenter Double-Blind Randomized Placebo-Controlled Trial of Infigratinib for the Adjuvant Treatment of Subjects with Invasive Urothelial Carcinoma with Susceptible FGFR3 Genetic Alterations (PROOF302)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 GDC0077+Palbo+Fulv vs Placebo PIK3CA View
Description: A PHASE III RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY AND SAFETY OF GDC-0077 PLUS PALBOCICLIB AND FULVESTRANT VERSUS PLACEBO PLUS PALBOCICLIB AND FULVESTRANT IN PATIENTS WITH PIK3CA-MUTANT HOROMONE RECEPTOR-POSITIVE HER2-NEGATIVE LOCALLY ADVANCED OR METASTATIC BREAST CANCER (WO41554)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph 3 BYL719 + nabpax TNBC PIK3CA View
Description: EPIK-B3: A phase III multicenter randomized double-blind placebo-controlled study to assess the efficacy and safety of alpelisib (BYL719) in combination with nab-paclitaxel in patients with advanced triple negative breast cancer with either phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) mutation or phosphatase and tensin homolog protein (PTEN) loss without PIK3CA mutation (CBYL719H12301)
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph 3 NUC-1031+Cis vs Gem/Cis la/mBTC View
Description: A Phase III Open-Label Multi-Centre Randomised Study Comparing NUC-1031 plus Cisplatin to Gemcitabine plus Cisplatin in Patients with Previously Untreated Locally Advanced or Metastatic Biliary Tract Cancer (NuTide:121)
Indication:
Biliary Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 Sinti vs Placebo ESCC View
Description: A Multicenter Double-Blind Randomized Phase III Clinical Trial Evaluating the Efficacy and Safety of Sintilimab vs. Placebo in Combination with Chemotherapy for First-Line Treatment of Unresectable Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma (ORIENT-15)CIBI308A301
Indication:
Esophageal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph1b Ipatasertib + Atezo + Docetax mCRPC View
Description: A PHASE Ib OPEN-LABEL MULTICENTER STUDY EVALUATING THE SAFETY AND EFFICACY OF IPATASERTIB IN COMBINATION WITH ATEZOLIZUMAB AND DOCETAXEL IN METASTATIC CASTRATE RESISTANT PROSTATE CANCER (CO41792)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: I
Title:
Plasma test ColoRec Cancer View
Description: PREEMPT CRC: PREvention Employing a Multiomics Plasma-based Test for ColoRectal Cancer (FRNM-004)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Title:
Ph2 m7824 triple neg BC View
Description: (MS200647_0020) A Phase II Multicenter Open Label Study of Bintrafusp alfa (M7824) Monotherapy in Participants with HMGA2-expressing Triple Negative Breast Cancer
Indication:
Breast Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 Mirv Sora Epi Ova FTC View
Description: SORAYA: A Phase 3 Single Arm Study of Mirvetuximab Soravtansine in Advanced High-Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression (IMGN853-0417)
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 Mirv Sora Epi Ova FTC View
Description: SORAYA: A Phase 3 Single Arm Study of Mirvetuximab Soravtansine in Advanced High-Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression (IMGN853-0417)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph3 Mirv Sora Epi Ova FTC View
Description: SORAYA: A Phase 3 Single Arm Study of Mirvetuximab Soravtansine in Advanced High-Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression (IMGN853-0417)
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
PH3 Dara/Len vs Len NDMM View
Description: A Randomized Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Patients with Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant (54767414MMY3021)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: III
Title:
PH3 Plac Carbo Pacil Dura +/- Olap DUO-E View
Description: D9311C00001; GOG-3041; ENGOT-EN10: A Randomised Multicentre Double-blind Placebo-controlled Phase III Study of First-line Carboplatin and Paclitaxel in Combination with Durvalumab Followed by Maintenance Durvalumab with or without Olaparib in Patients with Newly Diagnosed Advanced or Recurrent Endometrial Cancer (DUO-E)
Indication:
Endometrial Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Ph2 Ublituximab+ Umbralisib+ Venetoc CLL View
Description: ULTRA-V: Phase 2 Study to Assess the Efficacy and Safety of Ublituximab in Combination with Umbralisib and Venetoclax (U2-V) in Subjects with Chronic Lymphocytic Leukemia (CLL)(U2-VEN-207)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph3 Fruq + Placebo CC (FRESCO-2) View
Description: A Global Multicenter Randomized Placebo-Controlled Phase 3 Trial to Compare the Efficacy and Safety of Fruquintinib Plus Best Supportive Care to Placebo Plus Best Supportive Care in Patients with Refractory Metastatic Colorectal Cancer (FRESCO-2) (2019-013-GLOB1)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR KEAP1/NRF2 NSCLC View
Description: CX-839-014 "KEAPSAKE": A Phase 2 Randomized Multicenter Double-blind Study of the Glutaminase Inhibitor Telaglenastat with Pembrolizumab and Chemotherapy versus Placebo with Pembrolizumab and Chemotherapy in First-line Metastatic KEAP1/NRF2-mutated Nonsquamous Non-Small Cell Lung Cancer (NSCLC)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR-PH3 pral(Blu-667) RET-fusion mNSCLC View
Description: A Randomized Open-Label Phase 3 Study of Pralsetinib versus Standard of Care for First Line Treatment of RET fusion-positive Metastatic Non-Small Cell Lung Cancer (BLU-667-2303)
Indication:
Lung Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
Biomarker DNA Defect Men Prostate View
Description: Biomarker Study to Determine Frequency of DNA-repair Defects in Men with Metastatic Prostate Cancer (64091742PCR0002)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Title:
Ph 3 Chemo +/- Pembro/Olap EOC View
Description: A Randomized Phase 3 Double-Blind Study of Chemotherapy With or Without Pembrolizumab Followed by Maintenance With Olaparib or Placebo for the First-Line Treatment of BRCA non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK7339-001/ENGOT-ov43/GOG-3036)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
PH3 Ven+G vs FCR/BR in Fit untreated CLL View
Description: A PROSPECTIVE OPEN-LABEL MULTICENTER RANDOMIZED PHASE III TRIAL TO COMPARE THE EFFICACY AND SAFETY OF A COMBINED REGIMEN OF OBINUTUZUMAB AND VENETOCLAX VERSUS FLUDARABINE CYCLOPHOSPHAMIDE AND RITUXIMAB (FCR)/ BENDAMUSTINE AND RITUXIMAB (BR) IN FIT PATIENTS WITH PREVIOUSLY UNTREATED CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) WITHOUT DEL (17P) OR TP53 MUTATION (CO41685)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: III
Title:
PH2 MM Carf Poma & dexa (KPd) View
Description: An Open-label Phase 2 Study Treating Subjects With First or Second Relapse of Multiple Myeloma with Carfilzomib Pomalidomide and Dexamethasone (KPd) (20180117)
Indication:
Myelomas
Location:
Texas Oncology-Canton
Phase: II
Title:
Ph 3 Irino Oxa Flu Leu Pac + GEM mPan View
Description: An open-label randomised multicentre phase III study of irinotecan liposome injection oxaliplatin 5-fluorouracil/leucovorin versus nab-paclitaxel plus gemcitabine in subjects who have not previously received chemotherapy for metastatic adenocarcinoma of the pancreas (D-US-60010-001)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR: PH2 Tuca+ Tras HER2+ CC View
Description: MOUNTAINEER: A Phase 2 Open Label Study of Tucatinib Combined with Trastuzumab in Patients with HER2+ Metastatic Colorectal Cancer (ACCRU-GI-1617 SGNTUC-017)
Indication:
Colon Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR: PH2 Tuca+ Tras HER2+ CC View
Description: MOUNTAINEER: A Phase 2 Open Label Study of Tucatinib Combined with Trastuzumab in Patients with HER2+ Metastatic Colorectal Cancer (ACCRU-GI-1617 SGNTUC-017)
Indication:
Rectal Cancer
Location:
Texas Oncology-Canton
Phase: II
Title:
PH2 Brentux+CHP In Tx Naive PTCL View
Description: A dual-cohort open-label phase 2 study of brentuximab vedotin and CHP (A+CHP) in the frontline treatment of subjects with peripheral T-cell lymphoma (PTCL) with less than 10% CD30 expression (SGN35-032)
Indication:
Hematologic
Location:
Texas Oncology-Canton
Phase: II
Title:
PH2 Brentux+CHP In Tx Naive PTCL View
Description: A dual-cohort open-label phase 2 study of brentuximab vedotin and CHP (A+CHP) in the frontline treatment of subjects with peripheral T-cell lymphoma (PTCL) with less than 10% CD30 expression (SGN35-032)
Indication:
Leukemia
Location:
Texas Oncology-Canton
Phase: II
Title:
PH2 Brentux+CHP In Tx Naive PTCL View
Description: A dual-cohort open-label phase 2 study of brentuximab vedotin and CHP (A+CHP) in the frontline treatment of subjects with peripheral T-cell lymphoma (PTCL) with less than 10% CD30 expression (SGN35-032)
Indication:
Lymphomas
Location:
Texas Oncology-Canton
Phase: II
Title:
STAR Ph3 Carbo/Pac NCMGA00012 MSCC View
Description: A Phase 3 Global Multicenter Double-Blind Randomized Study of Carboplatin-Paclitaxel With INCMGA00012 or Placebo in Participants With Inoperable Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Anal Canal Not Previously Treated With Systemic Chemotherapy (POD1UM-303/InterAACT 2) (INCMGA 0012-303)
Indication:
Anal Cancer
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR Ph3 Carbo/Pac NCMGA00012 MSCC View
Description: A Phase 3 Global Multicenter Double-Blind Randomized Study of Carboplatin-Paclitaxel With INCMGA00012 or Placebo in Participants With Inoperable Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Anal Canal Not Previously Treated With Systemic Chemotherapy (POD1UM-303/InterAACT 2) (INCMGA 0012-303)
Indication:
Carcinoid
Location:
Texas Oncology-Canton
Phase: III
Title:
STAR PH 2 ASG-22CE Urothelial Cancer View
Description: A study of enfortumab vedotin (ASG-22CE) as monotherapy or in combination with other anticancer therapies for the treatment of urothelial cancer (SGN22E-002)
Indication:
Bladder Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR PH 2 ASG-22CE Urothelial Cancer View
Description: A study of enfortumab vedotin (ASG-22CE) as monotherapy or in combination with other anticancer therapies for the treatment of urothelial cancer (SGN22E-002)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Canton
Phase: I/II
Title:
STAR PH3 Nirap Abira HRR mCSPC View
Description: A Phase 3 Randomized Placebo-controlled Double-blind Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants with Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)(67652000PCR3002)
Indication:
Prostate Cancer
Location:
Texas Oncology-Canton
Phase: III