Title:
STAR Ph2 Itacitinib +/- Ruxo in MF View
Description: INCB 39110-209, An Open-Label Phase 2 Study of Itacitinib (INCB039110) in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Subjects With Myelofibrosis
Indication:
Myelofibrosis
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR INCB054828 Urothelial FGF/FGFR View
Description: A Phase 2, Open-label, Single-Agent, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects with Metastatic or Surgically Unresectable Urothelial Carcinoma Haboring FGF/FGFR Alterations
Indication:
Bladder Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR INCB054828 Urothelial FGF/FGFR View
Description: A Phase 2, Open-label, Single-Agent, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects with Metastatic or Surgically Unresectable Urothelial Carcinoma Haboring FGF/FGFR Alterations
Indication:
Bladder Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
PacCarboBev +/-Atezo, 1L Ovrn IMagyn050 View
Description: A PHASE III, MULTICENTER, RANDOMIZED, STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB TO PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER - YO39523
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph3 Nivo+Rucap Ovarian (ATHENA) View
Description: Clovis CO-338-087/GOG-3020/ENGOT-ov45/NCRI/ATHENA: A Multicenter, Randomized, Double-Blind, Placebo Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph 1b/2 SVB-S6-500 + Doxorubicin Ovarian View
Description: A Phase 1b/2 Randomized, Controlled Study of AVB-S6-500 in Combination with Pegylated Liposomal Doxorubicin or Paclitaxel in Patients with Platinum-resistant Recurrent Ovarian Cancer (AVB500-OC-002)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph3 Avelumab Ovarian JAVELIN 100 PARP View
Description: A RANDOMIZED, OPEN-LABEL, MULTICENTER, PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF AVELUMAB IN COMBINATION WITH CHEMOTHERAPY FOLLOWED BY MAINTENANCE THERAPY OF AVELUMAB IN COMBINATION WITH THE POLY (ADENOSINE DIPHOSPHATE [ADP]-RIBOSE) POLYMERASE (PARP) INHIBITOR TALAZOPARIB IN PATIENTS WITH PREVIOUSLY UNTREATED ADVANCED OVARIAN CANCER (JAVELIN OVARIAN PARP 100)(B9991030)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
STAR Ph2 enfortumab (ASG-22CE)Urothelial View
Description: A single-arm, open-label, multicenter study of enfortumab vedotin (ASG-22CE) for treatment of patients with locally advanced or metastatic urothelial cancer who previously received immune checkpoint inhibitor (CPI) therapy - SGN22E-001
Indication:
Bladder Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Ph3 Pembro + BCG High-risk Bladder View
Description: A Phase 3, Randomized, Comparator-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination with Bacillus Calmette- Guerin (BCG) in Participants with High-risk Non-muscle Invasive Bladder Cancer (HR NMIBC) that is Persistent or Recurrent Following BCG Induction (KEYNOTE-676)
Indication:
Bladder Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
PacCarboBev +/-Atezo, 1L Ovrn IMagyn050 View
Description: A PHASE III, MULTICENTER, RANDOMIZED, STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB TO PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER - YO39523
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Brain Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Ph3 Nivo+Rucap Ovarian (ATHENA) View
Description: Clovis CO-338-087/GOG-3020/ENGOT-ov45/NCRI/ATHENA: A Multicenter, Randomized, Double-Blind, Placebo Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Breast Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
STAR Ph2 Rucaparib mCRPC (TRITON 2) View
Description: TRITON2: A Multicenter, Open-label Phase 2 Study of Rucaparib inPatients with Metastatic Castration-resistant Prostate Cancer Associated with Homologous Recombination Deficiency - CO-338-052
Indication:
Prostate Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Non-Interv study Palbo HR+/HER2 AdvBC View
Description: POLARIS: Palbociclib in Hormone Receptor Positive AdvancedBreast Cancer: A Prospective Multicenter Non-Interventional Study (A5481082)
Indication:
Breast Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Title:
STAR Rucaparib v PhysC mCRPC (TRITON3) View
Description: TRITON3: A Multicenter, Randomized, Open-label Phase 3 Study of Rucaparib versus Physician''s Choice of Therapy for Patients withMetastatic Castration-resistant Prostate Cancer Associated withHomologous Recombination Deficiency (CO-338-063)
Indication:
Prostate Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph3 Abemaciclib HR+ HER2- (monarchE) View
Description: (I3Y-MC-JPCF) monarchE: A Randomized, Open-Label, Phase 3 Study of Abemaciclib Combined with Standard Adjuvant Endocrine Therapy versus Standard Adjuvant Endocrine Therapy Alone in Patients with High Risk, Node Positive, Early Stage, Hormone Receptor Positive, Human Epidermal Receptor 2 Negative, Breast Cancer
Indication:
Breast Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
STAR Abirat+pred +/- abemaciclib mCRPC View
Description: A Phase 2, Randomized, Double-blind, Placebo-Controlled Study of Abiraterone Acetate Plus Prednisone with or without Abemaciclib in Patients with Metastatic Castration-Resistant Prostate Cancer (I3Y-MC-JPCM)
Indication:
Prostate Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Breast Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph3 BBI-608/FOLFIRI +/- Bev, 2L mCRC View
Description: CanStem303C: A Phase III Study of BBI-608 in combination with 5-Fluorouracil, Leucovorin, Irinotecan (FOLFIRI) in Adult Patients with Previously Treated Metastatic Colorectal Cancer (CRC)
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph 2/3 Nivo 1L mCRC View
Description: An Open-Label Exploratory Phase 2/3 Study of Nivolumab with Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Metastatic Colorectal Cancer (CA209-9X8)
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II/III
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Cervical Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
STAR Ph2 INCMGA00012 mSCAC View
Description: A Phase 2 Study of INCMGA00012 in Participants With Squamous Carcinoma of the Anal Canal Who Have Progressed Following Platinum-Based Chemotherapy
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Colon Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Ph3 BBI-608/FOLFIRI +/- Bev, 2L mCRC View
Description: CanStem303C: A Phase III Study of BBI-608 in combination with 5-Fluorouracil, Leucovorin, Irinotecan (FOLFIRI) in Adult Patients with Previously Treated Metastatic Colorectal Cancer (CRC)
Indication:
Colon Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph1 TSR-022 Adv Solid Tumors View
Description: A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors (4020-01-001)
Indication:
Colon Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Ph 2/3 Nivo 1L mCRC View
Description: An Open-Label Exploratory Phase 2/3 Study of Nivolumab with Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Metastatic Colorectal Cancer (CA209-9X8)
Indication:
Colon Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II/III
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Renal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Lenvat+ever/pemb vs sunit 1L RCC [CLEAR] View
Description: A Multicenter, Open-label, Randomized, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib in Combination with Everolimus or Pembrolizumab Versus Sunitinib Alone in First-Line Treatment of Subjects with Advanced Renal Cell Carcinoma(E7080-G000-307)(CLEAR)
Indication:
Renal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Colon Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Endometrial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Renal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Esophageal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Skin Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Solid Tumors
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
PacCarboBev +/-Atezo, 1L Ovrn IMagyn050 View
Description: A PHASE III, MULTICENTER, RANDOMIZED, STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB TO PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER - YO39523
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Solid Tumors
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph3 Nivo+Rucap Ovarian (ATHENA) View
Description: Clovis CO-338-087/GOG-3020/ENGOT-ov45/NCRI/ATHENA: A Multicenter, Randomized, Double-Blind, Placebo Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
Indication:
Fallopian Tube Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
STAR Ph3 BLU-285 vs Regorafenib GIST View
Description: An International, Multicenter, Open-label, Randomized, Phase 3 Study of BLU-285 vs Regorafenib in Patients with Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST)
Indication:
GI Stromal Tumor (GIST)
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
STAR INCB054828 Urothelial FGF/FGFR View
Description: A Phase 2, Open-label, Single-Agent, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects with Metastatic or Surgically Unresectable Urothelial Carcinoma Haboring FGF/FGFR Alterations
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR INCB054828 Urothelial FGF/FGFR View
Description: A Phase 2, Open-label, Single-Agent, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects with Metastatic or Surgically Unresectable Urothelial Carcinoma Haboring FGF/FGFR Alterations
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Head and Neck Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Head and Neck Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
STAR Ph2 enfortumab (ASG-22CE)Urothelial View
Description: A single-arm, open-label, multicenter study of enfortumab vedotin (ASG-22CE) for treatment of patients with locally advanced or metastatic urothelial cancer who previously received immune checkpoint inhibitor (CPI) therapy - SGN22E-001
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Liver Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Ph3b/4 Safety Nivo+Ipi 1L, 2L NSCLC View
Description: CA209-817: A Phase IIIb/IV Safety and Efficacy Trial of Flat Dose Nivolumab in Combination with Ipilimumab in Participants with Non-Small Cell Lung Cancer
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III/IV
Title:
Ph1 TSR-022 Adv Solid Tumors View
Description: A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors (4020-01-001)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
STAR Ph2 Poziotinib EGFR/HER2 NSCLC View
Description: A Phase 2 Study of Poziotinib in Patients with Non-Small Cell Lung Cancer (NSCLC), Locally Advanced or Metastatic, with EGFR or HER2 Exon 20 Insertion Mutation (ZENITH20) (SPI-POZ-202)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Ph3 Adj canakinumab NSCLC View
Description: A phase III, multicenter, randomized, double blind, placebo-controlled study evaluating the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) completely resected (R0) non-small cell lung cancer (NSCLC)(CACZ885T2301)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph1/2 pegzilarginase+Pembro ED SCLC View
Description: A Phase 1/2 study of pegzilarginase (AEB1102, Co-ArgI-PEG) incombination with pembrolizumab in the treatment of patientswith extensive disease (ED) small cell lung cancer (SCLC) (CAEB1102-101B)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
STAR Ph2 Brigatinib ALK+ NSCLC (TAK2002) View
Description: Brigatinib in Patients With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or Ceritinib (2002)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR Ph3 ALK+ mNSCLC (Brigatinib-3001) View
Description: Brigatinib-3001- A Phase 3 Randomized Open-label Study of Brigatinib (ALUNBRIG™) Versus Alectinib (ALECENSA®) in Advanced Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer Patients Who Have Progressed on Crizotinib (XALKORI®)
Indication:
Lung Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
STAR Brentux in older pts w/HL 1L View
Description: SGN35-015:A phase 2 open-label study of brentuximab vedotin in front-line therapy of Hodgkin lymphoma (HL) in adults age 60 and above
Indication:
Lymphomas
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR Ph1/2 Tazemetostat r/r DLBCL & FL View
Description: An Open-Label, Multicenter, Phase 1/2 Study of Tazemetostat (EZH2 Histone Methyl Transferase [HMT] Inhibitor) as a Single Agent in Subjects With Advanced Solid Tumors or With B Cell Lymphomas and Tazemetostat in Combination With Prednisolone in Subjects With Diffuse Large B Cell Lymphoma - E7438-G000-101
Indication:
Lymphomas
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Melanoma
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Melanoma
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Ph1 TSR-022 Adv Solid Tumors View
Description: A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors (4020-01-001)
Indication:
Melanoma
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Melanoma
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
STAR Ph2 Itacitinib +/- Ruxo in MF View
Description: INCB 39110-209, An Open-Label Phase 2 Study of Itacitinib (INCB039110) in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Subjects With Myelofibrosis
Indication:
Myelofibrosis
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
PacCarboBev +/-Atezo, 1L Ovrn IMagyn050 View
Description: A PHASE III, MULTICENTER, RANDOMIZED, STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB TO PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER - YO39523
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph3 Nivo+Rucap Ovarian (ATHENA) View
Description: Clovis CO-338-087/GOG-3020/ENGOT-ov45/NCRI/ATHENA: A Multicenter, Randomized, Double-Blind, Placebo Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph 1b/2 SVB-S6-500 + Doxorubicin Ovarian View
Description: A Phase 1b/2 Randomized, Controlled Study of AVB-S6-500 in Combination with Pegylated Liposomal Doxorubicin or Paclitaxel in Patients with Platinum-resistant Recurrent Ovarian Cancer (AVB500-OC-002)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph3 Avelumab Ovarian JAVELIN 100 PARP View
Description: A RANDOMIZED, OPEN-LABEL, MULTICENTER, PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF AVELUMAB IN COMBINATION WITH CHEMOTHERAPY FOLLOWED BY MAINTENANCE THERAPY OF AVELUMAB IN COMBINATION WITH THE POLY (ADENOSINE DIPHOSPHATE [ADP]-RIBOSE) POLYMERASE (PARP) INHIBITOR TALAZOPARIB IN PATIENTS WITH PREVIOUSLY UNTREATED ADVANCED OVARIAN CANCER (JAVELIN OVARIAN PARP 100)(B9991030)
Indication:
Ovarian Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Pancreatic Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
PacCarboBev +/-Atezo, 1L Ovrn IMagyn050 View
Description: A PHASE III, MULTICENTER, RANDOMIZED, STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB TO PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER - YO39523
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph3 Nivo+Rucap Ovarian (ATHENA) View
Description: Clovis CO-338-087/GOG-3020/ENGOT-ov45/NCRI/ATHENA: A Multicenter, Randomized, Double-Blind, Placebo Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
Indication:
Peritoneal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
STAR Ph2 Rucaparib mCRPC (TRITON 2) View
Description: TRITON2: A Multicenter, Open-label Phase 2 Study of Rucaparib inPatients with Metastatic Castration-resistant Prostate Cancer Associated with Homologous Recombination Deficiency - CO-338-052
Indication:
Prostate Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR Rucaparib v PhysC mCRPC (TRITON3) View
Description: TRITON3: A Multicenter, Randomized, Open-label Phase 3 Study of Rucaparib versus Physician''s Choice of Therapy for Patients withMetastatic Castration-resistant Prostate Cancer Associated withHomologous Recombination Deficiency (CO-338-063)
Indication:
Prostate Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
STAR Abirat+pred +/- abemaciclib mCRPC View
Description: A Phase 2, Randomized, Double-blind, Placebo-Controlled Study of Abiraterone Acetate Plus Prednisone with or without Abemaciclib in Patients with Metastatic Castration-Resistant Prostate Cancer (I3Y-MC-JPCM)
Indication:
Prostate Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Ph3 BBI-608/FOLFIRI +/- Bev, 2L mCRC View
Description: CanStem303C: A Phase III Study of BBI-608 in combination with 5-Fluorouracil, Leucovorin, Irinotecan (FOLFIRI) in Adult Patients with Previously Treated Metastatic Colorectal Cancer (CRC)
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Ph 2/3 Nivo 1L mCRC View
Description: An Open-Label Exploratory Phase 2/3 Study of Nivolumab with Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Metastatic Colorectal Cancer (CA209-9X8)
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II/III
Title:
STAR Ph2 INCMGA00012 mSCAC View
Description: A Phase 2 Study of INCMGA00012 in Participants With Squamous Carcinoma of the Anal Canal Who Have Progressed Following Platinum-Based Chemotherapy
Indication:
Rectal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Renal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Lenvat+ever/pemb vs sunit 1L RCC [CLEAR] View
Description: A Multicenter, Open-label, Randomized, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib in Combination with Everolimus or Pembrolizumab Versus Sunitinib Alone in First-Line Treatment of Subjects with Advanced Renal Cell Carcinoma(E7080-G000-307)(CLEAR)
Indication:
Renal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: III
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Renal Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Skin Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
Ph1 MSB0011359C Solid Tumors View
Description: A Phase I, open-label, multiple-ascending dose trial to investigate the safety, tolerability, pharmacokinetics, biological and clinical activity of MSB0011359C in subjects with metastatic or locally advanced solid tumors and expansion to selected indications - EMD Serono EMR 200647-001
Indication:
Solid Tumors
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Solid Tumors
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
PhIb/2 Lenvatinib (E7080)+Pembro Solids View
Description: A Multicenter, Open-Label Phase 1b/2 Trial of Lenvatinib (E7080) Plus Pembrolizumab in Subjects With Selected Solid Tumors (E7080-A001-111)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II
Title:
STAR INCB054828 Urothelial FGF/FGFR View
Description: A Phase 2, Open-label, Single-Agent, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects with Metastatic or Surgically Unresectable Urothelial Carcinoma Haboring FGF/FGFR Alterations
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR INCB054828 Urothelial FGF/FGFR View
Description: A Phase 2, Open-label, Single-Agent, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects with Metastatic or Surgically Unresectable Urothelial Carcinoma Haboring FGF/FGFR Alterations
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
STAR Ph2 enfortumab (ASG-22CE)Urothelial View
Description: A single-arm, open-label, multicenter study of enfortumab vedotin (ASG-22CE) for treatment of patients with locally advanced or metastatic urothelial cancer who previously received immune checkpoint inhibitor (CPI) therapy - SGN22E-001
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: II
Title:
Phase 1/2a BMS-986253 + Nivo View
Description: A Phase 1/2a Study of BMS-986253 in Combination with Nivolumab in Advanced Cancers (CA027002)
Indication:
Urothelial Cancer
Location:
Texas Oncology-Fort Worth Cancer Center
Phase: I/II