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John C. Hardaway, M.D., Ph.D., FACS

General Summary

John C. Hardaway, M.D., Ph.D., FACS, clinical practice is primarily focused on cancers of the gastrointestinal tract, including diseases of the esophagus, stomach, liver, and pancreas. However, he also treats patients with thyroid, breast, and skin/soft tissue cancers. When possible, Dr. Hardaway uses the DaVinci robotic surgery platform to perform minimally invasive surgical procedures, which allow his patients to recover faster with less pain and shorter hospital stays.

Dr. Hardaway earned his M.D. and Ph.D. degrees at the University of Missouri in Columbia, where he attended medical school and was trained as a cellular immunologist. From there he was a general surgery resident at the University of Washington in Seattle and at Michigan State University before completing a fellowship in Complex General Surgical Oncology at Roger Williams Medical Center/Boston University in Providence, Rhode Island. As a result, he is double board-certified in general surgery and surgical oncology.

Outside of his surgical practice, Dr. Hardaway serves as an immunotherapy consultant, where he is focused on developing novel immunotherapies against solid tumors, to include multiple active clinical trials. 


  • Fellowship in Surgical Oncology
    Boston University, Boston, MA and Roger Williams Medical Center, Providence, RI
  • Residency in General Surgery, Chief Resident
    Michigan State University, East Lansing, MI
  • Internship in General Surgery
    University of Washington, Seattle, WA
  • Medical Doctorate
    University of Missouri, Columbia, MO
  • Doctor of Philosophy, Molecular Microbiology and Immunology
    University of Missouri, Columbia, MO

Accolades & Memberships

  • American Association of Immunologists
  • Americas Hepato-Pancreato-Biliary Association
  • Dr. E.L. Priest M.D./Ph.D. Scholarship (2008-2012)
  • Fellow of the American College of Surgeons
  • Life Sciences Fellowship, University of Missouri (2003-2008)
  • Richard E. Dean, MD Resident Research Award (2017)
  • Society for Immunotherapy of Cancer
  • Society of American Gastrointestinal and Endoscopic Surgeons
  • Society of Surgical Oncology
  • Tom and Anne Smith MD/PhD Student Award (2012)

Surgery Locations

  • HCA Houston Healthcare Kingwood
  • HCA Houston Healthcare Northwest
  • Houston Methodist Willowbrook Hospital
  • Memorial Hermann Northeast Hospital
  • Memorial Hermann The Woodlands Medical Center
  • St. Luke’s Health - The Woodlands Hospital


  • Breast Cancer
  • Esophageal Cancer
  • Gastric Cancer
  • Liver Cancer
  • Pancreatic Cancer
  • Sarcomas
  • Skin Cancer


  • Breast Cancer Resections, Oncoplastic Breast Reconstruction
  • Robotic/Minimally Invasive Gastric Cancer Surgery
  • Robotic/Minimally Invasive Liver Resection/Ablation
  • Robotic/Minimally Invasive Pancreas Surgery
  • Sarcoma Resection
  • Sentinel Lymph Node Biopsy
  • Skin Cancer Excision
  • Whipple Procedure (Pancreatoduodenectomy)

Research Interest

  • CAR-T Immunotherapy
  • Immunotherapy for Solid Tumors
  • Liver and Pancreatic Tumor Microenvironment
  • Regional Delivery of Therapeutics