Second Cancer Risk After Primary Cancer Treatment With Three-dimensional Conformal, Intensity-modulated, or Proton Beam Radiation Therapy

In a study of 450,373 pediatric and adult patients with a first cancer diagnoses between 2004 and 2015 who received 3-dimensional conformal radiotherapy, intensity-modulated radiotherapy (IMRT), or proton beam therapy, overall, the incidence of a second cancer diagnosis was less likely to occur in patients whose primary cancer was treated with proton beam therapy.