Second Cancer Risk After Primary Cancer Treatment With Three-dimensional Conformal, Intensity-modulated, or Proton Beam Radiation Therapy
In a study of 450,373 pediatric and adult patients with a first cancer diagnoses between 2004 and 2015 who received 3-dimensional conformal radiotherapy, intensity-modulated radiotherapy (IMRT), or proton beam therapy, overall, the incidence of a second cancer diagnosis was less likely to occur in patients whose primary cancer was treated with proton beam therapy.
In a study of 450,373 pediatric and adult patients with a first cancer diagnoses between 2004 and 2015 who received 3-dimensional conformal radiotherapy, intensity-modulated radiotherapy (IMRT), or proton beam therapy, overall, the incidence of a second cancer diagnosis was less likely to occur in patients whose primary cancer was treated with proton beam therapy. There was no overall difference in the risk of second cancer in patients who received 3-dimensional conformal radiotherapy versus IMRT.