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Efficacy and Safety of Locoregional Radiotherapy With Chemotherapy vs Chemotherapy Alone in De Novo Metastatic Nasopharyngeal Carcinoma: A Multicenter Phase 3 Randomized Clinical Trial

Research continues to demonstrate the crucial role of radiation therapy in cancer care.
Publication

JAMA Oncology

July 23, 2020

Contributed by:

You, Rui, et al.

Research continues to demonstrate the crucial role of radiation therapy in cancer care.  New research demonstrates that even in patients with the most advanced nasopharyngeal carcinomas who have isolated metastasis, there is a benefit for adding local radiation therapy.  In this recent study they use the most advanced radiation technique available to them, IMRT, however patients in Texas have an even more advanced radiation technique to reduce toxicity and extend life by using proton therapy, a specialized form of radiation therapy that excels at the treatment of nasopharyngeal carcinoma.  Prior studies have demonstrated that proton therapy has superior dosimetry and should allow these most advanced patients to get their treatment with as little toxicity as possible so they can continue their lives with minimal residual side effects.