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Phase 1 Study of MRX34, a Liposomal miR-34a Mimic, in Patients With Advanced Solid Tumours
British Journal of Cancer, 2020
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Phase I Dose-Escalation Trial of the Oral AKT Inhibitor Uprosertib in Combination With the Oral MEK1/MEK2 Inhibitor Trametinib in Patients With Solid Tumors
Cancer Chemotherapy and Pharmacology, 2020
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A Phase Ib, Open-Label, Dose-Escalation Study of the Safety and Pharmacology of Taselisib (GDC-0032) in Combination With Either Docetaxel or Paclitaxel in Patients With HER2-Negative, Locally Advanced, or Metastatic Breast Cancer
Breast Cancer Research and Treatment, 2019
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Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer
The New England Journal of Medicine, 2019
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Open-Label Study To Evaluate Trifluridine/Tipiracil Safety, Tolerability and Pharmacokinetics in Patients With Advanced Solid Tumours and Hepatic Impairment
British Journal of Clinical Pharmacology, 2019
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Targeting LIF-Mediated Paracrine Interaction for Pancreatic Cancer Therapy and Monitoring
Nature, 2019
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Genome-wide Discovery and Identification of a Novel miRNA Signature for Recurrence Prediction in Stage II and III Colorectal Cancer
Clinical Cancer Research, 2018
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Locally Advanced Carcinosarcoma of the Pancreas
Proceedings (Baylor University. Medical Center), 2018
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Pembrolizumab Versus Paclitaxel for Previously Treated, Advanced Gastric or Gastro-oesophageal Junction Cancer (KEYNOTE-061): a Randomised, Open-label, Controlled, Phase 3 Trial
The Lancet, 2018
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Genome-wide Discovery and Identification of a Novel miRNA Signature for Recurrence Prediction in Stage II and III Colorectal Cancer
Clinical Cancer Research, 2018
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Extended Dosing With CC-486 (Oral Azacitidine) in Patients With Myeloid Malignancies
American Journal of Hematology, 2018
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Phase 1/1b Dose Escalation and Expansion Study of BEZ235, a Dual PI3K/mTOR Inhibitor, in Patients With Advanced Solid Tumors Including Patients With Advanced Breast Cancer
Cancer Chemotherapy and Pharmacology, 2018
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Genome-Wide Discovery and Identification of a Novel miRNA Signature for Recurrence Prediction in Stage II and III Colorectal Cancer
Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 2018
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A Phase 1, Open-Label, Randomized, Crossover Study Evaluating the Bioavailability of TAS-102 (Trifluridine/Tipiracil) Tablets Relative to an Oral Solution Containing Equivalent Amounts of Trifluridine and Tipiracil
Journal of Clinical Pharmacology, 2017
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Effect of Everolimus on the Pharmacokinetics of Octreotide Long-Acting Repeatable in Patients With Advanced Neuroendocrine Tumors: An Analysis of the Randomized Phase III RADIANT-2 Trial
Clinical Pharmacology and Therapeutics, 2017
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Patient-reported Symptoms of Tenosynovial Giant Cell Tumors
Clinical Therapeutics, 2016
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A Phase I Study of the Safety, Pharmacokinetics and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in patients with Advanced Cancer
Clinical Cancer Research, 2016
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A Phase I Clinical Trial of ASG-5ME, a Novel Drug-antibody Conjugate Targeting SLC44A4, in Patients with Advanced Pancreatic and Gastric Cancers
Investigational New Drugs, 2016
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Randomized Phase 1 Crossover Study Assessing the Bioequivalence of Capsule and tTablet formulations of Dovitinib (TKI258) in Patients with Advanced Solid Tumors
Cancer Chemotherapy and Pharmacology, 2016
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Phase I Study of CHK1 Inhibitor LY2603618 in Combination with Gemcitabine in Patients with Solid Tumors
Oncology, 2016
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A Phase I Trial of Panobinostat (LBH589) in Patients with Metastatic Melanoma
Cancer Medicine, 2016
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An Innovative, Multi-arm, Complete Phase 1b Study of the Novel Anti-cancer Agent Tasisulam in Patients with Advanced Solid Tumors
Investigational New Drugs, 2015
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Phase I Study of the MEK Inhibitor Trametinib in Combination with the AKT Inhibitor Afuresertib in Patients with Solid Tumors and Multiple Myeloma
Cancer Chemotherapy and Pharmacology, 2015
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Clinical Safety and Immunogenicity of Tumor-Targeted, Plant-Made Id-KHL Conjugate Vaccines for Follicular Lymphoma
BioMed Research International, 2015
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Figitumumab in Patients with Refractory Metastatic Colorectal Cancer Previously Treated with Standard Therapies: a Nonrandomized, Open-label, Phase II Trial
Cancer Chemotherapy and Pharmacology, 2014
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A Phase I Dose-escalation Study of MEDI-575, a PDGFRα Monoclonal Antibody, in Adults with Advanced Solid Tumors
Cancer Chemotherapy and Pharmacology, 2014
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Phase 2 Trial of Afatinib, an ErbB Family Blocker, in Solid Tumors Genetically Screened for Target Activation
Cancer, 2013
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A Phase II Study with Cetuximab and Radiation Therapy with Surgically Resectable Esophageal and GE Junction Carcinomas: Hoosier Oncology Group G05-92
Journal of Thoracic Oncology, 2013
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Safety. Pharmacokinetic, Pharmacodynamic, and Efficacy Data for the Oral MEK Inhibitor Trametinib: a Phase I Dose-escalation Trial
Lancet Oncology, 2012
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Gemcitabine Plus Enzaustarin or Single-agent Gemcitabine in Locally Advanced or Metastatic Pancreatic Cancer: Results of a Phase II, Randomized, Noncomparative Study
Investigational New Drugs, 2011
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Referral Patterns and Adjuvant Chemotherapy use in Patients With Stage II Colon Cancer
Clinical Colorectal Cancer, 2011
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Anti-inflammatory Triterpenoid Blocks Immune Suppressive Function of MDSCs and Improves Immune Response in Cancer
Clinical Cancer Research, 2010
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Phase I Dose Escalation Study with Irinotecan, Capecitabine, Epirubicin, and Granulocyte Colony-stimulating Factor Support for Patients with Solid Malignancies
American Journal of Clinical Oncology, 2008
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The Continuum of Care: a Paradigm for the Management of Metastatic Colorectal Cancer
Oncologist, 2007
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Adverse Effects of Bevacizumab and Their Management in Solid Tumors
Supportive Cancer Therapy, 2006
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Efficacy of Sequential Treatment of HCT116 Colon Cancer Monolayers and Aenografts with Docetaxel, Flavopiridol, and 5-fluorouracil
Acta Pharmacologica Sinica, 2006
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A Phase II Clinical and Pharmacokinetic Study of Intravenous Exatecan Mesylate (DX-8951f) in Patients with Untreated Metastasis Gastric Cancer
Investigational New Drugs, 2005
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Dissecting Role of Regulatory Factors in NF-kB Pathway with siRNA
Acta Pharmacologica Sinica, 2005
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Selective Identification of Secreted and Transmembrane Breast Cancer Markers using Escherichia Coli Ampicillin Secretion Trap
Cancer Research, 2005
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A Phase II Study of Intravenous Exatecan Administered Daily for 5 Days, Every 3 Weeks to Patients With Biliary Tract Cancers
American Journal of Clinical Oncology, 2005
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IҝB Kinase α(IKKα) Regulates Sub-cellular Distribution and Turnover of Cyclin D1 by Phosphorylation
Journal of Biological Chemistry, 2005
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Enhanced Chemosensitivity to Irinotecan by RNA Interference Mediated Down-regulation of the NF-kB p65 Subunit
Clinical Cancer Research, 2004
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Irinotecan, Epirubicin, and Capecitabine in Metastatic Adenocarcinomas: Preliminary Results of a Phase I Study
Oncology (Williston Park), 2004
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Identification and Validation of Genes Involved in the Pathogenesis of Colorectal Cancer Using cDNA Microarrays and RNA Interference
Clinical Cancer Research, 2003
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Small Interfering RNAs Directed Against B-Catenin Inhibit the In-vitro and In-vivo Growth of Colon Cancer Cells
Clinical Cancer Research, 2003
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Increased Toxicity and Lack of Efficacy of Rofecoxib in Combination with Chemotherapy for Treatment of Metastatic Colorectal Cancer: A Phase II Study
International Journal of Cancer, 2003
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Phase II Study of Pemetrexed Disodium (Alimta(R)) Administered with Oral Folic Acid in Patients with Advanced Gastric Cancer
Annals of Oncology, 2003
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Reversible Renal Toxicity Resulting From high single Doses of the New Radiosensitizer Gadolinium Texaphyrin
American Journal of Clinical Oncology, 2000
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A Phase I Single-Dose Trial of Gadolinium Texaphyrin (Gd-Tex), a Tumor Selective Radiation Sensitizer Detectable by Magnetic Resonance Imaging
Clinical Cancer Research, 1999
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Palmitoyl-Protein Thioesterase Deficiency in a Novel Granular Variant of Late Infantile Neuronal Ceroid Lipofuscinosis
Pediatric Neurology, 1998
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Mutations in the Palmitoyl Protein Thioesterase Gene (PPT;CLN1) Causing Juvenile Neuronal Ceroid Lipofuscinosis with Granular Osmiophilic Deposits
Human Molecular Genetics, 1998
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Molecular Genetics of Palmitoyl Protein Thioesterase Deficiency in the U.S.
Journal of Clinical Investigation, 1998