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Frankie Ann Holmes, M.D.

General Summary

Dr. Holmes is board certified in internal medicine and also medical oncology. My professional career has involved the treatment and research for the cure of breast cancer. At MD Anderson, I completed my cancer training and joined the Faculty of Breast Medical Oncology. At MD Anderson, I performed the first clinical trial of paclitaxel (Taxol) resulting in approval for breast cancer. After 15 years at MD Anderson, I joined Texas Oncology/The US Oncology Network and the Breast Cancer Research Committee. I was the principal investigator for the clinical trial that led to the approval of pegfilgrastim (Neulasta) for prevention of low white blood cells from chemotherapy. I have continued as an active member of the Breast Cancer Research Committee with The US Oncology Network. Additionally, I am very involved in Supportive Care issues and lecture regularly on nausea, vomiting, myelosuppression. I am a Program Director for the School of Breast Oncology, an national annual comprehensive course updating physicians on breast cancer as well as The Future of Breast Cancer, a national breast cancer meeting aimed at disseminating information about new treatments and technologies for breast cancer. At Memorial City Hospital, once a month I coordinate and prepare a multidisplinary discussions about difficult, challenging, or new aspects of breast cancer. This requires close coordination with Radiology, Radiation Oncology, Pathology, and Surgery and its subspecialties.


College of William and Mary, Williamsburg, Virginia; BS in Chemistry; Phi Beta Kappa; Medical College of Virginia, Richmond, Virginia; Fellowship in Medical Oncology, MD Anderson Cancer Center, Houston, TX; Breast Medical Oncology Faculty, Associate Professor, MD Anderson Cancer Center.

Medical Practice

Other Information

Accolades & Memberships

American Society of Clinical Oncology; American Association of Therapeutic Radiation and Oncology, American Medical Association, American Association for the Advancement of Science; American Association for Cancer Research; European Society of Medical Oncology; American Society of Breast Diseases; American College of Physicians; Texas Society of Medical Oncology; Harris County Medical Association.

Community Service

Research Interest