• Request an Appointment
    Texas Oncology is ready to help you fight cancer. To schedule your first appointment, call 1-888-864-4226 or request an appointment online. Learn More.
  • Find a cancer center
    Texas Oncology has more than 150 treatment centers throughout Texas and southeastern Oklahoma. Use the map below to search for Texas Oncology centers close by. Learn More.
  • Find a physician
    Texas Oncology is a group more than 375 physicians focused on treating cancer and blood disorders. No matter where you may live in Texas or Southeastern Oklahoma, we have a physician near you. Learn More.
  • Clinical Trials
    Clinical trials allow you to access new, experimental treatments before they are widely available. Learn More.

Lymphoma Classification

Classification of Non-Hodgkin Lymphomas

The purpose of further classifying non-Hodgkin lymphomas into specific categories is to describe the individual behavior and develop appropriate treatment strategies for each type of lymphoma. Non-Hodgkin lymphomas have been classified by several different systems over the past 30 years. The most common system used in the 1980’s-1990’s was the International Working Formulation (IWF). The IWF divided non-Hodgkin lymphomas into 3 grades based on the lymphoma’s appearance under a microscope. Since the IWF was utilized, a great deal of additional work has been performed that further classifies non-Hodgkin lymphomas into individual cancers, each with their own specific features and behavior. This newer system is called the Revised European American Lymphoma (REAL) classification and has been recommended for use by all doctors. Unfortunately, it will take several years for all doctors and the results of clinical trials to refer to the REAL system. This section allows patients to select the relevant type of non-Hodgkin lymphoma and learn about its treatment.

International Working Formulation Classification of Non-Hodgkin’s Lymphoma

High Grade:

  • Lymphoblastic Lymphoma
  • Small Noncleaved cell, Burkitt’s or non Burkitt’s

Intermediate Grade:

Low Grade:

  • Small Lymphocytic/Chronic Lymphocytic Leukemia

Revised European American Lymphoma (REAL) Classification

  • B-Cell Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia
  • Lymphoplasmacytic Lymphoma
  • Mantle Cell Lymphoma
  • Marginal Zone B-Cell Lymphoma
  • MALToma
  • Burkitt’s Lymphoma
  • Burkitt’s Like Lymphoma
  • Precursor B or T-Cell Lymphoblastic Lymphoma/Leukemia

Copyright ©; 2015 Omni Health Media. All Rights Reserved.